Abstract Objective The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.

Abstract Objective The aim of this study was to compare the bone resorption rate, histomorphometry and immunohistochemical findings of bioactive glass (Biogran; Biomet, Warsaw, IN, USA) mixed with autogenous bone grafts (1:1) and autogenous bone graft isolate in maxillary sinus elevation surgery. Material and Methods A total of 9 maxillary sinuses were grafted with Biogran with autogenous bone graft (group 1) and 12 were mixed with autogenous bone graft (group 2). Postoperative cone beam computed tomography (CBCT) was used to measure the initial graft volume after 15 days (T1), and 6 months later, another CBCT scan was performed to evaluate the final graft volume (T2) and determine the graft resorption rate. The resorption outcomes were 37.9%±18.9% in group 1 and 45.7%±18.5% in group 2 (P=0.82). After 6 months, biopsies were obtained concurrent with the placement of dental implants; these implants were subjected to histomorphometric analysis and immunohistochemical analysis for tartrate-resistant acid phosphatase (TRAP). Results The average bone formation in group 1 was 36.6%±12.9 in the pristine bone region, 33.2%±13.3 in the intermediate region, and 45.8%±13.8 in the apical region; in group 2, the values were 34.4%±14.4, 35.0%±13.9, and 42.0%±16.6 of new bone formation in the pristine bone, intermediate, and apical regions, respectively. Immunostaining for TRAP showed poor clastic activity in both groups, which can indicate that those were in the remodeling phase. Conclusions The similarity between the groups in the formation and maintenance of the graft volume after 6 months suggests that the bioactive glass mixed with autogenous bone (1:1) can be used safely as a bone substitute for the maxillary sinus lift.

ResumoIntroduçãoEnxertos ósseos retirados da sínfise ou do ramo mandibular podem ser empregados para reconstrução de defeitos localizados dos maxilares, para permitir a instalação adequada de implantes dentários.ObjetivoEste estudo tem por objetivo avaliar a ocorrência de complicações associadas com as áreas doadoras e receptoras de enxerto ósseo mandibular, e a sobrevivência de implantes dentários instalados nesses sítios reconstruídos.Material e métodoAvaliaram-se 730 prontuários de pacientes submetidos a tratamento com implantes dentários. Desse universo, 72 pacientes, de ambos os gêneros, foram submetidos à reconstrução óssea com enxerto retirado da sínfise ou do ramo mandibular.ResultadoForam observadas 13 complicações e não houve diferença estatística significante quanto à ocorrência de complicações das áreas doadoras e receptoras, e da sobrevivência de implantes dentários instalados nos sítios reconstruídos com enxerto ósseo mandibular.ConclusãoOs enxertos ósseos mandibulares permitem a reconstrução de defeitos localizados dos maxilares e não são fatores de risco para a falha de implantes dentários.

AbstractIntroductionGrafts bone removed of the symphysis or mandibular ramus can be used for reconstruction located defect jaws to allow adequate installation of dental implants.ObjectiveThis study aims evaluate the occurrence of complications associated with donor and receptor sites of mandibular bone graft and survival of dental implants these reconstructed sites.Material and methodEvaluated seven hundred thirty records of patients submitted treatment with dental implants. This universe, seventy-two patients of both genders, was submitted bone reconstruction with graft removed from the symphysis or the mandibular ramus.ResultThirteen complications were observed and there was no statistically significant difference in the occurrence of complications of donor and recipient areas and survival of dental implants installed in sites reconstruction with mandibular bone graft.ConclusionThe mandibular bone grafts allow the reconstruction of defects located in jaws and don't risk factors for failure of dental implants.

INTRODUÇÃO: O cisto dentígero é o segundo cisto odontogênico mais frequente nos maxilares. É uma lesão benigna, derivada do epitélio odontogênico da coroa de um dente não erupcionado, porém de etiopatogenia incerta. São geralmente radiotransparentes e, mais comumente, uniloculares. Estas lesões são observadas em exames de rotina ou quando não ocorre o irrompimento de um dente permanente. Os terceiros molares inferiores e os caninos superiores são os dentes mais acometidos, sendo também alta a ocorrência desta lesão em dentes supranumerários e associados a odontomas. O cisto dentígero ocorre principalmente nas três primeiras décadas de vida, tendo um crescimento lento e assintomático; pode atingir dimensões consideráveis, causando deformidade facial, impactação e deslocamento de dentes e/ou estruturas adjacentes. OBJETIVO: Definição das técnicas de marsupialização e enucleação, bem como consideração de critérios objetivos importantes para o plano de tratamento, como tamanho do cisto, idade, proximidade com estruturas anatômicas e importância clínica do dente envolvido. Apesar das peculiaridades clínicas de cada caso e do método de tratamento escolhido, o prognóstico destas lesões é favorável, quando se emprega apropriada terapêutica. MATERIAL E MÉTODO: O presente estudo apresentará um relato de caso tratado através da manobra de descompressão seguida de enucleação, bem como uma discussão acerca das modalidades de tratamento. RESULTADO: O paciente encontra-se em pós-operatório de dois anos sem sinais de recidiva da lesão e ausência de parestesias em face. CONCLUSÃO: A técnica empregada preservou a função neurossensorial e mostrou-se eficiente para a cura da lesão.

INTRODUCTION: The dentigerous cyst is the second most common odontogenic cyst in the jaws. It is a benign lesion of odontogenic epithelium derived from the crown of a tooth that has not erupted, but of uncertain etiology. They are generally radiolucent and usually unilocular. These lesions are observed in routine examinations or when the eruption of a permanent tooth is delayed. The third molars and maxillary canines are the most affected teeth, and also the high occurrence of this lesion is associated with supernumerary teeth and odontomas. The dentigerous cyst occurs mainly in the first three decades of life, It's growth is slow, asymptomatic and can reach considerable size causing facial deformity, displacement and impaction of teeth and/or surrounding structures. OBJECTIVE: Definition of marsupialization and enucleation techniques as well as consideration of important objective criteria for the treatment plan like cyst size, age, proximity to anatomical structures and clinical importance of the involved tooth. Despite the clinical peculiarities of each case and the chosen treatment method, the prognosis of these lesions are favorable when appropriate therapy is used. MATERIAL AND METHOD: This study will present a case report treated by maneuver of decompression followed by enucleation and discussion of treatment modalities. RESULT: The patient is on two years of postoperative without signs of relapse and absence of paresthesias in the face. CONCLUSION: The technique preserved the neurosensory function and was effective for the extinction of the lesion.

Although the search for the ideal bone substitute has been the focus of a large number of studies, autogenous bone is still the gold standard for the filling of defects caused by pathologies and traumas, and mainly, for alveolar ridge reconstruction, allowing the titanium implants installation. OBJECTIVES: The aim of this study was to evaluate the dynamics of autogenous bone graft incorporation process to surgically created defects in rat calvaria, using epifluorescence microscopy. MATERIAL AND METHODS: Five adult male rats weighing 200-300 g were used. The animals received two 5-mm-diameter bone defects bilaterally in each parietal bone with a trephine bur under general anesthesia. Two groups of defects were formed: a control group (n=5), in which the defects were filled with blood clot, and a graft group (n=5), in which the defects were filled with autogenous bone block, removed from the contralateral defect. The fluorochromes calcein and alizarin were applied at the 7th and 30th postoperative days, respectively. The animals were killed at 35 days. RESULTS: The mineralization process was more intense in the graft group (32.09%) and occurred mainly between 7 and 30 days, the period labeled by calcein (24.66%). CONCLUSIONS: The fluorochromes showed to be appropriate to label mineralization areas. The interfacial areas between fluorochrome labels are important sources of information about the bone regeneration dynamics.

Hemangiomas são tumores benignos da infância que se caracterizam por uma fase de crescimento rápido com proliferação de células endoteliais, ocorrendo em 10 a 12% das crianças com 1 ano de idade. Sua localização mais comum é nos lábios, na língua, mucosa jugal e no palato. Aproximadamente 50% dos casos de hemangioma mostram completa resolução e 90% deles resolvem-se até os 9 anos de idade. As complicações ocorrem em apenas 20% dos casos e o problema mais comum é a ulceração com ou sem infecção. O tratamento depende da localização, do tamanho e do estágio evolutivo da lesão, bem como da idade do paciente. A cirurgia geralmente é indicada quando não há resposta aos tratamentos sistêmicos ou por razões estéticas, podendo ser empregada sob forma de exérese simples com ou sem plástica. Este artigo apresenta um caso de hemangioma cavernoso labial em uma criança de 4 anos de idade, a qual, devido ao tamanho da lesão, foi submetida a 3 sessões de esclerose vascular seguido de exérese simples da lesão, com acompanhamento clínico de 2 anos de pós-operatório.

Hemangiomas are benign tumors of infancy and childhood, characterized by a phase of fast growth with endothelial cell proliferation, occurring in 10-12% of children at 1 year of age. It is known that hemangiomas of infancy are most commonly located on the head and neck region (around 60% of cases) and occur more frequently in the lips, tongue, and palate. Approximately 50% of hemangiomas have complete resolution, and 90% of them are resolved up to the age of 9. Complications occur in only 20% of the cases, the most common problem being ulceration with or without infection. The treatment depends on lesion location, size and evolution stage, and the patient's age. Surgery is usually indicated when there is no response to systemic treatments, or even for esthetic reasons, being performed as a simple excision in combination or not with plastic surgery. This paper reports a case of lip cavernous hemangioma in a 4-year-old child, who was submitted to 3 sessions of vascular sclerosis due to the size of the lesion, before undergoing simple excision of the hemangioma. Two years of postoperative clinical follow-up shows treatment success with no recurrence of the lesion.

FUNDAMENTOS - Adesivos teciduais têm sido muito usados para síntese de ferida, em função de ser um método indolor, rápido e de fácil execução. OBJETIVOS -Analisar e comparar compatibilidade dos adesivos, etil- cianoacrilato (Super Bonder) e butilcianoacrilato (Histoacryl), e a reparação de incisões em dorso de ratos entre o fio de sutura e os respectivos adesivos. MÉTODOS - Foram usados 15 ratos. Realizaram-se duas lojas cirúrgicas no dorso. Em cada uma, foi implantado um tubo de polietileno (10mm x 1mm), os quais foram preenchidos com os adesivos Super Bonder (lado direito) e Histoacryl (lado esquerdo). As incisões, do lado esquerdo, foram coaptadas com Super Bonder, e as do lado direito, com Histoacryl. Uma incisão mediana, entre as duas incisões,foi realizada e suturada com fio de seda. Os animais foram mortos, depois de 7(sete), 35(trinta) e 120 (cento e vinte dia) dias. RESULTADOS: Os adesivos usados, no presente estudo, não promoveram reação inflamatória, quando usados para síntese das incisões. Porém, estes adesivos, quando implantados no subcutâneo, promoveram reação inflamatória até 120 (cento e vinte dia) dias, no entanto, a reação é mais intensa com Histoacryl. CONCLUSÕES: Super Bonder e Histoacryl permitem o processo cicatricial dos tecidos incisados; facilitam a sutura das incisões. Desta forma, estes podem ser utilizados para sínteses de feridas, lacerações ou incisões cutâneas.

BACKGROUND: Tissue adhesives have been used for the synthesis of wound due to their painless application and quick and easy handling. OBJECTIVES: The purpose of this study was to analyze and compare the compatibility of the adhesives ethylcyanoacrylate (Super Bonder) and butyl-cyanoacrylate (Histoacryl), and to compare the reparation of incisions in the dorsum of rats with suture and the respective adhesives. METHODS: Fifteen rats were used. Two surgical pockets were created in their dorsum. A polyethylene tube (10mm x 1mm) was implanted in each one. Each tube was filled with the adhesives Super Bonder(left side) and Histoacryl (right side). The incisions on the left side were closed with Super Bonder, and the incisions on the right side, with Histoacryl. A median incision between the two other incisions was made and closed with braided silk suture. The animals were killed after, 7, 35 and 120 days. RESULTS: The adhesives used in the present study did not promote inflammatory reaction when used for the synthesis of incisions. However, when implanted subcutaneously, they caused an inflammatory reaction within 120 days. Reaction is more severe with Histoacryl. CONCLUSIONS: Super Bonder and Histoacryl can be used effectively in the healing of incised tissues; they aid in the suture of incisions. However, these adhesives can be used for the synthesis of wounds, lacerations or cutaneous incisions.